Protein Details: Potassium voltage-gated channel subfamily F member 1

Protein ID

ICDB_Pro_1508

Protein Name

Potassium voltage-gated channel subfamily F member 1

Gene Name

KCNF1

Organism

Homo sapiens (Human)

Length

494 amino acids

AlphaFoldDB

AF-Q9H3M0-F1-model_v4.pdb

Function

Putative voltage-gated potassium channel

Sequence

MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLLTEEKHHRTRLQSCK

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Prostate Cancer and Bladder Leiomyoma

Location

Detected in heart; brain; liver; skeletal muscle; kidney and pancreas.

DOI ID

10.1006/bbrc.1997.7830; 10.1038/nature03466; 10.1101/gr.2596504; 10.1016/s0008-6363(02)00602-8

RefSeq

NP_002227.2